Signs & Symptoms

In the early stages of kidney disease, most people have no symptoms. Finding protein in the urine is the earliest sign of damage to the kidneys from diabetes. That’s why it’s important to have your healthcare provider test your urine for protein once a year.

Small amounts of protein in urine is called “microalbuminuria.” Over time, the amount of protein in the urine may increase, causing foam to develop on the surface of the toilet water during urination.

Loss of protein from the blood may result in the buildup of fluid under the skin in the feet and ankles (edema). The feet and ankles will become enlarged and pressing on them will create a temporary dent in their surface.

Other symptoms of kidney disease can include loss of sleep, poor appetite, upset stomach, weakness, itchy skin and difficulty concentrating. These symptoms often do not show up until kidney disease is in an advanced stage.